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WHAT IS Pgx TESTING?: Personalized Medicine
How Pgx Testing is Beneficial
Pharmacogenomics is the study of how your genes affect the way your body responds to certain medicines. Genetics affect how your body processes and breaks down medicines. Differences in these genetics can be the reason some people benefit greatly from a particular medication while some show no benefit at all. Genetics can also be the reason why some people have serious side effects to certain medications. Pharmcogenomics testing provides information about your genetic makeup provides information about your genes to help your healthcare provider choose the medicine and dosage that are the "best fit" for you.Pharmacogenomics is a type of precision medicine.
Pgx Testing Steps
Pgx Testing Steps and FAQ Discussion
Pharmacogenomic (PGx) testing analyzes a patient's genetic makeup to predict how they will respond to certain medications. This information can help healthcare providers choose the most effective and safest medications and dosages for individual patients, potentially reducing adverse drug reactions and improving treatment outcomes.
1. Consultation and Ordering:
- Consultation with a Healthcare Provider: Discuss the potential benefits and limitations of PGx testing with a doctor to determine if it's appropriate for you.
- Test Ordering: If deemed necessary, your healthcare provider will order the PGx test, specifying the genes to be analyzed based on your medical history and current or potential medications.
2. Sample Collection:
- Sample Collection Process:
- Cheek Swab: A healthcare professional or you (with at-home kits) will gently rub the inside of your cheek with a special swab.
3. Laboratory Analysis:
- DNA Extraction and Purification: The DNA is extracted from the collected sample and purified in the laboratory.
- Genotyping: The purified DNA undergoes analysis to identify specific genetic variations (variants) in the genes of interest.
- Reporting: The laboratory generates a report that includes the identified genetic variants and their potential impact on drug metabolism and response.
4. Results Interpretation and Application:
- Review by Healthcare Provider: Your healthcare provider will review the PGx test results and discuss them with you.
- Integration with Clinical Information: The PGx results are interpreted in the context of your medical history, current medications, and other relevant factors.
- Medication Management: Based on the PGx results and other clinical information, your healthcare provider may adjust your medication regimen, including drug selection and dosage.
Important Considerations:
- Limitations: PGx testing is not a perfect predictor of drug response, as other factors like age, overall health, and organ function can also influence how your body responds to medications.
- Cost and Insurance Coverage: The cost of PGx testing and insurance coverage can vary. Check with us at the laboratory.